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H index (50) Papers

Synthesis and in vitro evaluation of novel coumarin�chalcone hybrids as potential anticancer agents

Koneni V. Sashidhara*, Abdhesh Kumar, Manoj Kumar, Jayanta Sarkar, Sudhir Sinha

Bioorganic & medicinal chemistry letters, 2010, 20 (24), 7205-7211
Citations
392

Rare dipeptide and urea derivatives from roots of Moringa oleifera as potential anti-inflammatory and antinociceptive agents

Koneni V. Sashidhara*, Jammikuntla N. Rosaiah, Ethika Tyagi, Rakesh Shukla, Ram Raghubir, Siron M. Rajendran

European journal of medicinal chemistry, 2009, 44 (1), 432-436
Citations
184

Discovery and synthesis of novel 3-phenylcoumarin derivatives as antidepressant agents

Koneni V. Sashidhara*, Manoj Kumar, Ram K. Modukuri, Anuj Srivastava, Anju Puri

Bioorganic & medicinal chemistry letters, 2011, 21 (7), 1937-1941
Citations
171

Synthesis and antihyperlipidemic activity of novel coumarin bisindole derivatives

Koneni V. Sashidhara*, Abdhesh Kumar, Manoj Kumar, Anuj Srivastava, Anju Puri

Bioorganic & Medicinal Chemistry Letters, 2010, 20 (22), 6504-6507
Citations
162

Identification of quinoline-chalcone hybrids as potential antiulcer agents

Koneni V. Sashidhara*, Srinivasa Rao Avula, Vaibhav Mishra, Gopal Reddy Palnati, L. Ravithej Singh, Neetu Singh, Yashpal S. Chhonker, Priyanka Swami, R.S. Bhatta, Gautam Palit.

European journal of medicinal chemistry, 2015, 89, 638-653
Citations
129

Discovery of coumarin-monastrol hybrid as potential antibreast tumor-specific agent

Koneni V. Sashidhara*, Srinivasa Rao Avula, Komal Sharma, Gopala Reddy Palnati, Surendar Reddy Bathul*

European journal of medicinal chemistry, 2013, 60, 120-127
Citations
125

Synthesis and anti-inflammatory activity of novel biscoumarin�chalcone hybrids

Koneni V. Sashidhara*, Manoj Kumar, Ram K. Modukuri, Ravi Sonkar, Gitika Bhatia, A.K. Khanna, Shivika Rai, Rakesh Shukla

Bioorganic & medicinal chemistry letters, 2011, 21 (15), 4480-4484
Citations
109

Induction of mitochondrial dysfunction and oxidative stress in Leishmania donovani by orally active clerodane diterpene

Manoj Kathuria , Arindam Bhattacharjee , Koneni V. Sashidhara, Suriya Pratap Singh, Kalyan Mitra *.

Antimicrobial agents and chemotherapy, 2014, 58 (10), 5916-5928
Citations
106

Indole-based fibrates as potential hypolipidemic and antiobesity agents

Koneni V. Sashidhara*, Manoj Kumar, Ravi Sonkar, Bhanu Shankar Singh, A. K. Khanna, Gitika Bhatia

Journal of Medicinal Chemistry, 2012, 55 (6), 2769-2779
Citations
101

Novel keto-enamine Schiffs bases from 7-hydroxy-4-methyl-2-oxo-2H-benzo [h] chromene-8, 10-dicarbaldehyde as potential antidyslipidemic and antioxidant agents

Koneni V. Sashidhara*, Jammikuntla N. Rosaiah, Gitika Bhatia, J.K. Saxena

European journal of medicinal chemistry, 2008, 43 (11), 2592-2596
Citations
101

16??Hydroxycleroda?3,13 (14)Z?dien?15,16?olide from�Polyalthia longifolia: a safe and orally active antileishmanial agent

Pragya Misra, Koneni V Sashidhara*, Suriya P. Singh, Awanish Kumar, Reema Gupta, Shailendra S Chaudhaery, Souvik Sen Gupta, HK Majumder, Anil K Saxena, Anuradha Dube*

British journal of pharmacology, 2010, 159 (5), 1143-1150
Citations
99

A selective account of effective paradigms and significant outcomes in the discovery of inspirational marine natural products

Koneni V. Sashidhara, Kimberly N. White and Phillip Crews*

Journal of natural products, 2009, 72 (3), 588-603
Citations
90

Novel Chalcone�Thiazole Hybrids as Potent Inhibitors of Drug Resistant�Staphylococcus aureus

Koneni V. Sashidhara*, K. Bhaskara Rao, Pragati Kushwaha, Ram K. Modukuri, Pratiksha Singh, Isha Soni, P. K. Shukla, Sidharth Chopra and Mukesh Pasupuleti.

ACS medicinal chemistry letters, 2013, 6 (7), 809-813
Citations
85

Discovery of coumarin�dihydropyridine hybrids as bone anabolic agents

Koneni V. Sashidhara*, Manoj Kumar, Vikram Khedgikar, Priyanka Kushwaha, Ram K. Modukuri, Abdhesh Kumar, Jyoti Gautam, Divya Singh, Balasubramaniam Sridhar, and Ritu Trivedi*

Journal of Medicinal Chemistry, 2013, 56 (1), 109-122
Citations
84

Coumarin chalcone fibrates: a new structural class of lipid lowering agents

Koneni V. Sashidhara*, Gopala Reddy Palnati, Ravi Sonkar, Srinivasa Rao Avula, Chetan Awasthi, Gitika Bhatia

European journal of medicinal chemistry, 2013, 64, 422-431
Citations
83

Discovery and synthesis of novel substituted benzocoumarins as orally active lipid modulating agents

Koneni V. Sashidhara*, Manoj Kumar, Ram K. Modukuri, Anuj Srivastava, Anju Puri

Bioorganic & medicinal chemistry letters, 2011, 21 (22), 6709-6713
Citations
82

Anti-tumour activity of a novel coumarin�chalcone hybrid is mediated through intrinsic apoptotic pathway by inducing PUMA and altering Bax/Bcl-2 ratio

Neetu Singh, Jayanta Sarkar*, Koneni V. Sashidhara, Shakir Ali, Sudhir Sinha*

Apoptosis, 2014, 19 (6), 1017-1028
Citations
80

Synthesis and evaluation of novel triazolyl quinoline derivatives as potential antileishmanial agents

AkankshaUpadhyay, Pragati Kushwaha, SampaGupta, Ranga Prasad Dodda, Karthik Ramalingam, Ruchir Kant, NeenaGoyal, Koneni V.Sashidhara*

European Journal of Medicinal Chemistry, 2018, 154, 172-181
Citations
78

Coumarin�trioxane hybrids: Synthesis and evaluation as a new class of antimalarial scaffolds

Koneni V. Sashidhara*, Abdhesh Kumar, Ranga Prasad Dodda, Naikade Niraj Krishna, Pooja Agarwal, Kumkum Srivastava, S.K. Puri

Bioorganic & medicinal chemistry letters, 2012, 22 (12), 3926-3930
Citations
77

A novel route to synthesis of flavones from salicylaldehyde and acetophenone derivatives

Koneni V. Sashidhara*, Manoj Kumar, Abdhesh Kumar

Tetrahedron Letters, 2012, 53 (18), 2355-2359
Citations
77

Antiplasmodial activity of novel keto-enamine chalcone-chloroquine based hybrid pharmacophores

Koneni V. Sashidhara*, Manoj Kumar, Ram K. Modukuri, Rajeev Kumar Srivastava, Awakash Soni, Kumkum Srivastava, Shiv Vardan Singh, J.K. Saxena, Harsh M. Gauniyal, Sunil K. Puri

Bioorganic & medicinal chemistry, 2012, 20 (9), 2971-2981
Citations
76

Design and synthesis of new series of coumarin�aminopyran derivatives possessing potential anti-depressant-like activity

Koneni V. Sashidhara *, Ram K. Modukuri, Seema Singh, K. Bhaskara Rao, G. Aruna Teja, Sampa Gupta, Shubha Shukla.

Bioorganic & Medicinal Chemistry Letters, 2015, 25 (2), 337-341
Citations
75

Antidyslipidemic and antioxidative activities of 8-hydroxyquinoline derived novel keto-enamine Schiffs bases

Koneni V. Sashidhara*, Abdhesh Kumar, Gitika Bhatia, M.M. Khan, A.K. Khanna, J.K. Saxena

European journal of medicinal chemistry, 2009, 44 (4), 1813-1818
Citations
74

Coumarin�benzimidazole hybrids as a potent antimicrobial agent: synthesis and biological elevation

L. Ravithej Singh,Srinivasa Rao Avula, Sneha Raj, Akanksha Srivastava,Gopala Reddy Palnati, Tripathi CKM, Mukesh Pasupuleti*,Koneni V. Sashidhara*

The Journal of antibiotics, 2017, 70 (9), 954-961
Citations
73

Novel coumarin derivatives as potential antidyslipidemic agents

Koneni V. Sashidhara*, Abdhesh Kumar, Manoj Kumar, Ravi Sonkar, Gitika Bhatia, A.K. Khanna

Bioorganic & medicinal chemistry letters, 2010, 20 (14), 4248-4251
Citations
72

Essential oil composition of�Matricaria recutita�L. from the lower region of the Himalayas

Koneni V. Sashidhara*, RS Verma, P Ram

Flavour and fragrance journal, 2006, 21 (2), 274-276
Citations
72

Molecular Iodine Catalysed One-Pot Synthesis of Chromeno[4,3-b]quinolin-6-ones under Microwave Irradiation

Koneni V. Sashidhara *, Gopala Reddy Palnati, L. Ravithej Singh, Amit Upadhyay, Srinivasa Rao Avula, Abdhesh Kumar and Ruchir Kant

Green Chemistry, 2015, 17 (7), 3766-3770
Citations
70

Galactolipids from Bauhinia racemosa as a new class of antifilarial agents against human lymphatic filarial parasite, Brugia malayi

Koneni V. Sashidhara*, Suriya P. Singh, Sweta Misra, Jyoti Gupta, Shailja Misra-Bhattacharya

European journal of medicinal chemistry,2012, 50, 230-235
Citations
70

The marine sponge metabolite mycothiazole: A novel prototype mitochondrial complex I inhibitor

J. Brian Morgan, Fakhri Mahdi, Yang Liu, Veena Coothankandaswamy, Mika B. Jekabsons, Tyler A. Johnson, Koneni V. Sashidhara, Phillip Crews, Dale G. Nagle*, Yu-Dong Zhou*

Bioorganic & medicinal chemistry, 2010, 18 (16), 5988-5994
Citations
70

Synthesis, Biological Evaluation, Structure?Activity Relationship and Mechanism of Action Studies of Quinoline-metronidazole Derivatives against Experimental Visceral Leishmaniasis

Akanksha Upadhyay, Pragya Chandrakar, Sampa Gupta, Naveen Parmar, Sandeep Kumar Singh, Mamunur Rashid, Pragati Kushwaha, M. Wahajuddin, Koneni V. Sashidhara* and Susanta Kar*

Journal of Medicinal Chemistry, 2019, 62 (11), 5655-5671
Citations
68

Analysis of taxol and major taxoids in Himalayan yew, Taxus wallichiana

Shashi Bala, G.C Uniyal*, S.K Chattopadhyay, V Tripathi, K. V. Sashidhara, M Kulshrestha, R.P Sharma, S.P Jain, A.K Kukreja, S Kumar

Journal of Chromatography A, 1999 858 (2), 239-244
Citations
68

Isolation and identification of beta-hematin inhibitors from Flacourtia indica as promising antiplasmodial agents

Koneni V. Sashidhara*, Suriya P. Singh, Shiv Vardan Singh, Rajeev K. Srivastava, Kumkum Srivastava, J.K. Saxena, Sunil K. Puri

European journal of medicinal chemistry, 2013, 60, 497-502
Citations
67

Lipid lowering agents of natural origin: An account of some promising chemotypes

Suriya P. Singh and Koneni V. Sashidhara*

European Journal of Medicinal Chemistry, 2017, 140, 331-348
Citations
66

Synthesis of novel benzocoumarin derivatives as lipid lowering agents

Koneni V. Sashidhara*, Jammikuntla N. Rosaiah, Abdhesh Kumar, Gitika Bhatia, A.K. Khanna

Bioorganic & medicinal chemistry letters, 2010, 20 (10), 3065-3069
Citations
63

Synthesis and bio-evaluation of indole-chalcone based benzopyrans as promising antiligase and antiproliferative agents

Sampa Gupta, Pooja Maurya, Akanksha Upadhyay, Pragati Kushwaha, Shagun Krishna, Mohammad Imran Siddiqi, Koneni V. Sashidhara*, Dibyendu Banerjee*

European journal of medicinal chemistry, 2018, 143, 1981-1996
Citations
62

Cytotoxic clerodane diterpenoids from the leaves of Polyalthia longifolia

Koneni V. Sashidhara*, Suriya P. Singh, Jayanta Sarkar, Sudhir Sinha

Natural product research, 2010, 24 (18), 1687-1694
Citations
62

Antimicrobial evaluation of clerodane diterpenes from Polyalthia longifolia var. pendula

Koneni V. Sashidhara*, Suriya P. Singh, P.K. Shukla

Natural Product Communication, 2009 4 (3), 327-330
Citations
62

Hybrid benzofuran�bisindole derivatives: New prototypes with promising anti-hyperlipidemic activities

Koneni V. Sashidhara*, Ram K. Modukuri,Ravi Sonkar, K. Bhaskara Rao, Gitika Bhatia

European Journal of Medicinal Chemistry, 2013, 68, 38-46
Citations
61

Synthesis and in vitro evaluation of new chloroquine-chalcone hybrids against chloroquine-resistant strain of Plasmodium falciparum

Koneni V. Sashidhara*, Srinivasa Rao Avula, Gopala Reddy Palnati, Shiv Vardan Singh, Kumkum Srivastava, Sunil K. Puri, J.K. Saxena

Bioorganic & medicinal chemistry letters, 2012, 22 (17), 5455-5459
Citations
61

Neo-tanshinlactone inspired synthesis, in vitro evaluation of novel substituted benzocoumarin derivatives as potent anti-breast cancer agents

Koneni V. Sashidhara*, Jammikuntla N. Rosaiah, Manoj Kumar, Rishi Kumar Gara, Lakshma Vadithe Nayak, Kamini Srivastava, Hemant Kumar Bid, Rituraj Konwar

Bioorganic & medicinal chemistry letters, 2010, 20 (23), 7127-7131
Citations
61

Various dereplication strategies using LC-MS for rapid natural product lead identification and drug discovery

Koneni V. Sashidhara*, Jammikuntla N. Rosaiah

Natural product communications, 2007, 2 (2), 1934578X0700200218
Citations
61

Synthesis, biological evaluation and molecular dynamic simulations of novel Benzofuran-tetrazole derivatives as potential agents against Alzheimer�s disease

Pragati Kushwaha, Soobiya Fatima, Akanksha Upadhyay, Sampa Gupta, Sudha Bhagwati, TanviBaghel, M. I. Siddiqi, Aamir Nazir, Koneni V. Sashidhara*

Bioorganic & medicinal chemistry letters, 2019, 29 (1), 66-72
Citations
58

Cytotoxic cycloartane triterpene and rare isomeric bisclerodane diterpenes from the leaves of Polyalthia longifolia var. pendula

Koneni V. Sashidhara*, Suriya P. Singh, Ruchir Kant, Prakas R. Maulik, Jayanta Sarkar, Sanjeev Kanojiya, K. Ravi Kumar

Bioorganic & medicinal chemistry letters, 2010, 20 (19), 5767-5771
Citations
57

Cell growth inhibitory action of an unusual labdane diterpene, 13?epi?sclareol in breast and uterine cancers�in vitro

Koneni V. Sashidhara*, Jammikuntla N. Rosaiah, Abdhesh Kumar, Hemant K Bid, Rituraj Konwar, Naibedya Chattopadhyay

Phytotherapy Research, 2007,
Citations
55

Synthesis and antifilarial activity of chalcone�thiazole derivatives against a human lymphatic filarial parasite, Brugia malayi

Koneni V. Sashidhara *, K. Bhaskara Rao, Vikas Kushwaha, Ram K. Modukuri, Richa Verma, P.K. Murthy.*

European journal of medicinal chemistry, 2014, 81, 473-480
Citations
54

Identification of the antioxidant principles of Polyalthia longifolia var. pendula using TEAC assay

Koneni V. Sashidhara*, Suriya P. Singh, Anuj Srivastava, Anju Puri

Natural product research, 2011, 25 (9), 918-926
Citations
54

A facile and efficient Bi (III) catalyzed synthesis of 1, 1-dihydroperoxides and 1, 2, 4, 5-tetraoxanes

Koneni V. Sashidhara*, Srinivasa Rao Avula, L. Ravithej Singh, Gopala Reddy Palnati

Tetrahedron Letters, 2012, 53 (36), 4880-4884
Citations
53

Discovery of a new class of HMG-CoA reductase inhibitor from Polyalthia longifolia as potential lipid lowering agent

Koneni V. Sashidhara*, Suriya P. Singh, Anuj Srivastava, Anju Puri, Yashpal S. Chhonker, Rabi S. Bhatta, Priyanka Shah, Mohammad Imran Siddiqi

European journal of medicinal chemistry, 2011, 46 (10), 5206-5211
Citations
52

Design and synthesis of novel indole-chalcone fibrates as lipid lowering agents

Koneni V. Sashidhara *, Ranga Prasad Dodda, Ravi Sonkar, Gopala Reddy Palnati, Gitika Bhatia

European journal of medicinal chemistry, 2014, 81, 499-509
Citations
51

Efficient and general synthesis of 3-aryl coumarins using cyanuric chloride

Koneni V. Sashidhara*, Gopala Reddy Palnati, Srinivasa Rao Avula, Abdhesh Kumar

Synlett, 2012, (04), 611-621
Citations
50
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